3,4-Dichloroisocoumarin is a potent serine-protease and SrLip inhibitor (Ki for SrLip: 26.6 µM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms[1][2][3][4][5].
Molecular Weight:
215.03
Purity:
99.72
CAS Number:
[51050-59-0]
Formula:
C9H4Cl2O2
Target:
Apoptosis,Ser/Thr Protease
Application Notes:
MCE Product type: Reference compound1
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