WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2[1].
Molecular Weight:
498.46
Purity:
99.43
CAS Number:
[2247544-02-9]
Formula:
C18H21Cl2N9S2
Target:
E1/E2/E3 Enzyme
Application Notes:
MCE Product type: Reference compound
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