MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding assays. MTI-31 shows an IC50 of 39 nM for mTOR in LANCE assay of mTOR substrate phosphorylation with 100 µM ATP. MTI-31 can be used for the research of breast cancer[1].
Molecular Weight:
474.55
Purity:
99.98
CAS Number:
[1567915-38-1]
Formula:
C26H30N6O3
Target:
mTOR
Application Notes:
MCE Product type: Reference compound1
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