CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3alpha and GSK3beta, respectively. CHIR-98023 can improve insulin action and glucose metabolism[1][2].
Molecular Weight:
471.30
CAS Number:
[252916-76-0]
Formula:
C20H16Cl2N8O2
Target:
GSK-3
Application Notes:
Reference compound
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