Tolcapone 3-beta-D-glucuronide, CAS [[204853-33-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-126194
Supplier Catalog Number:
HY-126194
Alternative Catalog Number:
MCE-HY-126194-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Ro 61-1448
Tolcapone 3-beta-D-glucuronide (Ro 61-1448) is an O-methyl metabolite of Tolcapone (HY-17406) and is pharmacologically inactive. Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits alpha-syn and Abeta42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma[1][2][3][4][5].
Molecular Weight:
449.36
CAS Number:
[204853-33-8]
Formula:
C20H19NO11
Target:
Amyloid-beta,Apoptosis,COMT,Drug Metabolite,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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