Verproside, a catalpol derivative iridoid glycoside isolated from the genus Pseudolysimachion, represses TNF-alpha -induced MUC5AC expression by inhibiting NF-kappaB activation via the IKK/IkappaB signaling cascade. Verproside has potent anti-inflammatory, antioxidant, antinociceptive and anti-asthmatic activities. Verproside has the potential for the study of chronic obstructive pulmonary disease (COPD)[1].
Molecular Weight:
498.43
CAS Number:
[50932-20-2]
Formula:
C22H26O13
Target:
IKK,NF-kappaB,TNF Receptor
Application Notes:
MCE Product type: Natural Products
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