Tyk2-IN-7 is an orally active TYK2 JH2 inhibitor, binds to TYK2 JH2 domain with IC50 and Ki.app of 0.00053 µM and 0.00007 µM, respectively. Tyk2-IN-7 provides a highly selective alternative to conventional TYK2 orthosteric inhibitors, inhibits TYK2/JAK1/JAK2 kinase domain. Tyk2-IN-7 can inhibit the IL-23 and IFN-alpha signaling pathways. Tyk2-IN-7 is commonly used in the study of inflammatory conditions such as colitis[1][2].
Molecular Weight:
401.46
Purity:
99.62
CAS Number:
[1609391-90-3]
Formula:
C18H15D3N6O3S
Target:
IFNAR,Interleukin Related,JAK
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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