NPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death[1]. NPD-1335 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
455.55
Purity:
98.10
CAS Number:
[2376326-31-5]
Formula:
C28H29N3O3
Target:
Parasite,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound1
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