Z1609609733, CAS [[2375374-15-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-126278
Supplier Catalog Number:
HY-126278
Alternative Catalog Number:
MCE-HY-126278-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Z1609609733 is a 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 1.46 µM. Z1609609733 binds the adenine site of the NAD+ pocket of PHGDH in a reversible and non-covalent manner, inhibiting the first committed step of the serine synthesis pathway. Z1609609733 abrogates de novo serine synthesis and inhibits proliferation of cancer cells[1].
Molecular Weight:
596.46
CAS Number:
[2375374-15-3]
Formula:
C30H27Cl2N3O6
Target:
Phosphoglycerate Dehydrogenase (PHGDH)
Application Notes:
MCE Product type: Reference compound
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