GNE-618 is a potent, orally active nicotinamide phosphoribosyl transferase (NAMPT) inhibitor with an IC50 of 6 nM. GNE-618 depletes NAD levels and induces tumor cell death. Anti-tumor activity[1].
Molecular Weight:
460.43
Purity:
99.57
CAS Number:
[1362151-42-5]
Formula:
C21H15F3N4O3S
Target:
NAMPT
Application Notes:
MCE Product type: Reference compound
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