TCMDC-135051 hydrochloride is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 hydrochloride prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 hydrochloride has antiparasiticidal activity (EC50=320 nM)[1].
Molecular Weight:
508.05
Purity:
98.17
CAS Number:
[2705545-47-5]
Formula:
C29H34ClN3O3
Target:
Parasite
Application Notes:
Reference compound
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