UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA[1].
Molecular Weight:
847.09
CAS Number:
[2920299-34-7]
Formula:
C47H70N6O8
Target:
Histone Methyltransferase
Application Notes:
Reference compound
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