1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine, CAS [[27098-24-4]]
Biozol Catalog Number:
MCE-HY-126359
Supplier Catalog Number:
HY-126359
Alternative Catalog Number:
MCE-HY-126359-5MG,MCE-HY-126359-10MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
SLPC, 18:0-18:2 PC
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine (18:0/18:2 PC) is an endogenous phospholipid marker molecule in the glycerophospholipid metabolic pathway. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a core component of the phospholipid bilayer of biological membranes and a key responsive lipid for radiation injury and cardiometabolic diseases. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine constitutes the phospholipid bilayers of cell membranes and high-density lipoprotein (HDL), and regulates the core activity of lipoprotein functional homeostasis. The content of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine in mouse serum shows a significant dose-dependent decrease with increasing ionizing radiation dose, and its level in human HDL also decreases significantly in metabolic syndrome. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can serve as a biological dosimeter marker for ionizing radiation injury, and is used for rapid and accurate assessment of radiation absorbed dose in exposed individuals. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can also act as a lipidomics research target for cardiometabolic diseases such as lipid metabolic syndrome and early-onset coronary heart disease[1][2].
Molecular Weight:
786.11
Purity:
98
CAS Number:
[27098-24-4]
Formula:
C44H84NO8P
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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