(E/Z)-BCI (NSC 150117) is a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory activities. (E/Z)-BCI attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-kappaB pathway[1].
Molecular Weight:
317.42
CAS Number:
[15982-84-0]
Formula:
C22H23NO
Target:
Apoptosis,Phosphatase
Application Notes:
MCE Product type: Reference compound1
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