DM4-SPDP is a agent-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody agent conjugate[1]. SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3].
Molecular Weight:
981.57
Formula:
C45H61ClN4O14S2
Target:
Drug-Linker Conjugates for ADC,Microtubule/Tubulin
Application Notes:
ADC Related
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