Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1][2].
Molecular Weight:
494.54
Purity:
98.01
CAS Number:
[2704316-81-2]
Formula:
C25H28F2N8O
Target:
CDK,Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Reference compound1
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