Abemaciclib metabolite M18-d8 is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1][2].
Molecular Weight:
502.59
Purity:
99.87
Formula:
C25H20D8F2N8O
Target:
CDK,Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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