H-Val-Val-OH (Val-Val) is a stereochemistry-dependent substrate and inhibitor of apical oligopeptide transporters. H-Val-Val-OH undergoes apical intracellular accumulation in human intestinal cells via carrier-mediated transport, and inhibits the uptake of Cephalexin (HY-B0200) through interaction with transporters. Substitution of L-valine with D-valine in H-Val-Val-OH abolishes its binding ability to apical oligopeptide transporters[1].
Molecular Weight:
216.28
Purity:
99
CAS Number:
[3918-94-3]
Formula:
C10H20N2O3
Target:
Drug Intermediate,Oligopeptide Cotransporter
Application Notes:
MCE Product type: Reference compound
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