SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions[1][2].
Molecular Weight:
454.28
Purity:
99.57
CAS Number:
[3031-95-6]
Formula:
C13H19N4O12P
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Natural Products
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