AS2863619 (free base), CAS [[2241300-50-3]]

Product Overview

• Article Name: AS2863619 (free base), CAS [[2241300-50-3]]
• Biozol Catalog Number: MCE-HY-126675
• Supplier Catalog Number: HY-126675
• Alternative Catalog Number: MCE-HY-126675-5MG,MCE-HY-126675-50MG,MCE-HY-126675-100MG,MCE-HY-126675-10MMX1ML,MCE-HY-126675-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AS2863619 free base enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 free base is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene[1].

Product Properties

• Molecular Weight: 332.32
• Purity: 99.87
• CAS Number: [2241300-50-3]
• Formula: C16H12N8O
• Target: CDK,STAT

Application Notes

• Application Notes: MCE Product type: Reference compound