Apoptolidin is a polyketide isolated from Nocardiopsis bacteria[1]. Apoptolidin is a selective mitochondrial F1FO ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells[1][2].
Molecular Weight:
1129.37
Purity:
95.60
CAS Number:
[194874-06-1]
Formula:
C58H96O21
Target:
Apoptosis,ATP Synthase
Application Notes:
MCE Product type: Natural Products
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