DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody agent conjugate[1]. DBCO-(PEG2-VC-PAB-MMAE)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Molecular Weight:
2835.50
Purity:
99.21
CAS Number:
[2259318-55-1]
Formula:
C149H224N22O32
Target:
Drug-Linker Conjugates for ADC
Application Notes:
MCE Product type: ADC Related
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