Cholic acid 7-sulfate-d4, CAS [[1332881-66-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-126855S
Supplier Catalog Number:
HY-126855S
Alternative Catalog Number:
MCE-HY-126855S-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
7-Sulfocholic acid-d4
Cholic acid 7-sulfate-d4 (7-Sulfocholic acid-d4) is the deuterium labeled Cholic acid 7-sulfate (HY-126855). Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC50=0.17 µM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation[1][2].
Molecular Weight:
492.66
CAS Number:
[1332881-66-9]
Formula:
C24H36D4O8S
Target:
G protein-coupled Bile Acid Receptor 1,Isotope-Labeled Compounds,MHC
Application Notes:
MCE Product type: Isotope-Labeled Compounds
* VAT and and shipping costs not included. Errors and price changes excepted
