Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[1][2][3].
Molecular Weight:
450.55
Purity:
99.97
CAS Number:
[1260075-17-9]
Formula:
C24H26N4O3S
Target:
Pyruvate Kinase
Application Notes:
MCE Product type: Reference compound
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