AFG206 is a first-generation ATP competitive ''type II FLT3 inhibitor. AFG206 potently inhibits cell proliferation (IC50 around 0.1 µM) via induction of Apoptosis in FLT3-ITD-Ba/F3 cells and D835Y-Ba/F3 cells. AFG206 is promising for research of acute myeloid leukemia[1].
Molecular Weight:
333.38
CAS Number:
[630122-37-1]
Formula:
C20H19N3O2
Target:
Apoptosis,FLT3
Application Notes:
MCE Product type: Reference compound
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