RI(dl)-2 blocks RAD51s D-loop activity in biochemical systems with an IC50 value of 11.1 µM and inhibits homologous recombination (HR) activity with an IC50 value of 3.0 µM. RI(dl)-2 inhibits HR-mediated repair of DNA double strand breaks and sensitizes different cancer cell lines[1].
Molecular Weight:
287.36
CAS Number:
[1902146-75-1]
Formula:
C19H17N3
Target:
RAD51
Application Notes:
MCE Product type: Reference compound
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