RO5256390 is an orally effective trace amine associated receptor 1 (TAAR1) agonist. RO5256390 exhibits pro-cognitive and antidepressant-like properties in rodent and primate models, showing similar brain activation patterns to Olanzapine (HY-14541). RO5256390 blocks compulsive overeating behavior in rats. RO5256390 can inhibit ATP (HY-B2176)-induced TNF secretion in mouse bone marrow-derived macrophages[1][2][3].
Molecular Weight:
218.30
Purity:
98.75
CAS Number:
[1043495-96-0]
Formula:
C13H18N2O
Target:
Trace Amine-associated Receptor (TAAR)
Application Notes:
MCE Product type: Reference compound
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