Nigericin, CAS [[28380-24-7]]

Product Overview

• Article Name: Nigericin, CAS [[28380-24-7]]
• Biozol Catalog Number: MCE-HY-127019
• Supplier Catalog Number: HY-127019
• Alternative Catalog Number: MCE-HY-127019-5MG,MCE-HY-127019-100MG,MCE-HY-127019-25MG,MCE-HY-127019-10MMX1ML,MCE-HY-127019-10MG,MCE-HY-127019-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/beta-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC[1][2][3][4][5][6][7].

Product Properties

• Molecular Weight: 724.96
• Purity: 99.43
• CAS Number: [28380-24-7]
• Formula: C40H68O11
• Target: Antibiotic,Bacterial,NOD-like Receptor (NLR),Potassium Channel,Pyroptosis,Wnt,beta-catenin

Application Notes

• Application Notes: MCE Product type: Reference compound