Iptacopan (TFA), CAS [[1644670-38-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-127105B
Supplier Catalog Number:
HY-127105B
Alternative Catalog Number:
MCE-HY-127105B-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
LNP023 (TFA)
Iptacopan (LNP023) TFA is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan TFA exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan TFA can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)[1][2][3].
Molecular Weight:
536.55
CAS Number:
[1644670-38-1]
Formula:
C27H31F3N2O6
Target:
Complement System
Application Notes:
MCE Product type: Reference compound
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