ND-654 is a highly selective acetyl-CoA carboxylase (ACC) inhibitor (IC50: ACC1=3 nM, ACC2=8 nM). ND-654 reduces hepatic lipogenesis, decreases neutrophil recruitment and promotes anti-inflammatory M2 macrophage polarization. ND-654 is promising for research of nonalcoholic steatohepatitis and hepatocellular carcinoma[1].
Molecular Weight:
583.65
CAS Number:
[1434641-55-0]
Formula:
C29H33N3O8S
Target:
Acetyl-CoA Carboxylase
Application Notes:
MCE Product type: Reference compound1
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