SCR7 is an unstable form that can be autocyclized into a stable form SCR7 pyrazine (HY-107845). SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity[1][2].
Molecular Weight:
334.39
Purity:
98.22
CAS Number:
[1533426-72-0]
Formula:
C18H14N4OS
Target:
Apoptosis,CRISPR/Cas9,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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