QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 µM. QS11 activates Wnt/beta-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells[1].
Molecular Weight:
567.68
Purity:
99.10
CAS Number:
[944328-88-5]
Formula:
C36H33N5O2
Target:
Arf Family GTPase,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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