Losartan Carboxylic Acid (Standard), CAS [[124750-92-1]] Preis auf Anfrage

Catalog Number: MCE-HY-12765R
Article Name: Losartan Carboxylic Acid (Standard), CAS [[124750-92-1]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-12765R
Supplier Catalog Number: HY-12765R
Alternative Catalog Number: MCE-HY-12765R-25MG,MCE-HY-12765R-100MG,MCE-HY-12765R-5MG,MCE-HY-12765R-10MG,MCE-HY-12765R-50MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: E-3174 (Standard), EXP-3174 (Standard)
Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].
Molecular Weight: 436.89
CAS Number: [124750-92-1]
Formula: C22H21ClN6O2
Target: Angiotensin Receptor,Drug Metabolite,Reference Standards
Application Notes: MCE Product type: Reference Standards