Losartan-d4 (carboxylic acid), CAS [[1246820-62-1]] Preis auf Anfrage

Product Overview

• Article Name: Losartan-d4 (carboxylic acid), CAS [[1246820-62-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-12765S
• Supplier Catalog Number: HY-12765S
• Alternative Catalog Number: MCE-HY-12765S-1MG,MCE-HY-12765S-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: E-3174 D4, EXP-3174 D4

Product Description

Losartan-d4 carboxylic acid (E-3174-d4) is the deuterium labeled Losartan Carboxylic Acid (HY-12765). Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure.

Product Properties

• Molecular Weight: 440.92
• Purity: 98.09
• CAS Number: [1246820-62-1]
• Formula: C22H17D4ClN6O2
• Target: Angiotensin Receptor

Application Notes

• Application Notes: MCE Product type: Isotope-Labeled Compounds