Sotuletinib (BLZ945) is a potent, selective, orally active and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. Sotuletinib can be used for microglia depletion, and for tumor and CNS-related disease research[1][2][3][4].
Molecular Weight:
398.48
Purity:
99.97
CAS Number:
[953769-46-5]
Formula:
C20H22N4O3S
Target:
c-Fms
Application Notes:
MCE Product type: Reference compound
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