GF 15 is an inhibitor of centrosomal clustering during cell mitosis, with an EC50 value of 900 nM for inducing multipolar spindles. GF 15 is a derivative of griseofulvin that inhibits tubulin polymerization at concentrations above 25 µM. GF 15 inhibits tumor growth and significantly prolongs survival in mouse xenograft models of human colon cancer and multiple myeloma[1].
Molecular Weight:
428.86
CAS Number:
[888042-13-5]
Formula:
C23H21ClO6
Target:
Microtubule/Tubulin,Mitosis
Application Notes:
MCE Product type: Reference compound
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