PF-04856264 is a potent and selective Nav1.7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1.7, respectively. PF-04856264 has low potency against the rat Nav1.7 channel. PF-04856264 shows analgesic effect[1][2].
Molecular Weight:
437.49
Purity:
99.29
CAS Number:
[1235397-05-3]
Formula:
C20H15N5O3S2
Target:
Sodium Channel
Application Notes:
MCE Product type: Reference compound1
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