UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research[1].
Molecular Weight:
455.58
Purity:
99.68
CAS Number:
[892742-76-6]
Formula:
C20H17N5O2S3
Target:
Urea Transporter
Application Notes:
MCE Product type: Reference compound
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