UCCF-029 (free base), CAS [[2110-25-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-128131
Supplier Catalog Number:
HY-128131
Alternative Catalog Number:
MCE-HY-128131-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
UCCF-029 Free base is a potent activator of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. UCCF-029 Free base exhibits enhanced activity through benzannulation of the flavone A-ring at the 7,8-position. UCCF-029 Free base serves as a structural guide for the development of more effective flavonoid analogues. UCCF-029 Free base demonstrates improved potency compared to apigenin in activating wild-type CFTR. UCCF-029 Free base also exhibits potential for activating the mutant CFTR (G551D-CFTR) though not as robustly as apigenin.
Molecular Weight:
273.29
CAS Number:
[2110-25-0]
Formula:
C18H11NO2
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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