KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and the closely related isoform CLK4, with an IC50 of 16.5 nM for CLK1. KH-CB20 can also inhibit DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1].
Molecular Weight:
338.19
Purity:
99.80
CAS Number:
[1354448-60-4]
Formula:
C15H13Cl2N3O2
Target:
CDK,DYRK
Application Notes:
MCE Product type: Reference compound1
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