M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 µM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 µM[1].
Molecular Weight:
445.94
Purity:
99.05
CAS Number:
[1395048-49-3]
Formula:
C22H28ClN5O3
Target:
Pim
Application Notes:
MCE Product type: Reference compound1
* VAT and and shipping costs not included. Errors and price changes excepted