(R)-IDO/TDO-IN-1 (compound 25) is an indoleamine-2,3-dioxygenase (IDO) inhibitor, with good pharmacokinetic properties. (R)-IDO/TDO-IN-1 exhibits anti-tumor activity in MC38 xenograft model. (R)-IDO/TDO-IN-1 shows synergistic effect with anti-PD-1 monoclonal antibody (SHR-1210)[1].
Molecular Weight:
413.49
Purity:
98.04
CAS Number:
[2033173-00-9]
Formula:
C25H24FN5
Target:
Indoleamine 2,3-Dioxygenase (IDO)
Application Notes:
MCE Product type: Reference compound
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