MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 µM[1].
Molecular Weight:
441.71
Purity:
98.63
CAS Number:
[2374703-19-0]
Formula:
C19H16Cl3FN4O
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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