RO5454948 (Compound 9) is the inhibitor for Dyrk1B and Dyrk1A with IC50 of 68 nM and 22 nM. RO5454948 exhibits cytotoxicity in cancer cell SW620 with EC50 of 1.9 µM[1][2].
Molecular Weight:
498.32
Purity:
99.53
CAS Number:
[1386979-55-0]
Formula:
C23H17Cl2N5O4
Target:
DYRK
Application Notes:
MCE Product type: Reference compound1
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