KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM, F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity[1].
Molecular Weight:
459.01
Purity:
98.47
CAS Number:
[1303470-48-5]
Formula:
C21H27ClN8S
Target:
Ketohexokinase
Application Notes:
MCE Product type: Reference compound
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