UC-112 is a survivin and XIAP modulator with anticancer activity. UC-112 selectively downregulates and degrades survivin via the ubiquitin-mediated proteasomal degradation pathway. UC-112 reduces XIAP levels in in vivo tumor models. UC-112 activates caspase-3/7 and caspase-9, and induces cancer cell apoptosis. UC-112 is applicable to studies on melanoma, prostate cancer and cancer-related research[1][2].
Molecular Weight:
348.44
Purity:
98.92
CAS Number:
[383392-66-3]
Formula:
C22H24N2O2
Target:
Apoptosis,IAP
Application Notes:
MCE Product type: Reference compound
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