SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM, Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[1][2][3].
Molecular Weight:
562.98
Purity:
99.54
CAS Number:
[2702366-44-5]
Formula:
C28H30Cl3N3OS
Target:
Smo
Application Notes:
MCE Product type: Reference compound1
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