SAG (GMP) is SAG (HY-12848) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM, Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[1][2][3].
Molecular Weight:
490.06
CAS Number:
[912545-86-9]
Formula:
C28H28ClN3OS
Target:
Smo
Application Notes:
MCE Product type: GMP Small Molecules
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