DNK-333 is a potent and balanced dual NK1 and NK2 receptor antagonist with IC50 values of 4.8 nM and 5.5 nM, respectively. DNK-333 blocks the Neurokinin A (NKA) (HY-P0197)-induced bronchoconstriction in asthma[1].
Molecular Weight:
624.40
CAS Number:
[398507-81-8]
Formula:
C27H25Cl2F6N3O3
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound
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