D927, CAS [[2253733-37-6]]

Product Overview

• Article Name: D927, CAS [[2253733-37-6]]
• Biozol Catalog Number: MCE-HY-128574
• Supplier Catalog Number: HY-128574
• Alternative Catalog Number: MCE-HY-128574-10MMX1ML,MCE-HY-128574-50MG,MCE-HY-128574-10MG,MCE-HY-128574-25MG,MCE-HY-128574-100MG,MCE-HY-128574-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: DS11252927

Product Description

D927 (DS11252927) is an orally active glucose transporter type 4 (GLUT4) translocation activator with an EC50 of 0.14 µM. D927 enhances the binding affinity of PI3Kalpha catalytic subunit p110alpha to canonical RAS proteins (KRAS4A, KRAS4B) and RRAS, RRAS2, MRAS. D927 activates the PI3Kalpha-AKT pathway (increasing phosphorylation of AKT, p70S6 kinase) without affecting the RAF-ERK1/2 pathway. D927 improves hyperglycemia in type 1 and type 2 diabetes mice model. D927 can be used for the study of glucose homeostasis disorders and diabetes[1][2].

Product Properties

• Molecular Weight: 452.50
• Purity: 99.46
• CAS Number: [2253733-37-6]
• Formula: C23H21FN4O3S
• Target: Akt,GLUT,PI3K

Application Notes

• Application Notes: MCE Product type: Reference compound